Globanone
Globanone® stands apart from traditional musks. This biotech macrocyclic musk from Symrise, first produced in 2002, offers a clean, elegant scent profile that bridges the gap between natural ingredients and modern sustainable chemistry.

Character
How it smells
A biotech macrocyclic musk redefining sustainable fragrance
Globanone® is solid at room temperature and requires dilution before use in formulations.
Origin
United Kingdom
The journey to Globanone® reflects a broader evolution in fragrance chemistry. For centuries, perfumers relied solely on natural ingredients—plant extracts, animal secretions, and botanical materials.
The 19th century introduced organic synthesis, opening new creative possibilities. However, it took another 60 years after commercial organic synthesis began for the fragrance industry to successfully produce the first biotech-based perfumery ingredients at scale.
Symrise's breakthrough with Globanone® in 2002 marked a turning point: clean musk chemistry derived from biological processes rather than petrochemical routes. This innovation positioned macrocyclic musks as viable sustainable alternatives to traditional nitro and polycyclic musks, reshaping how perfumers approach scent design in an environmentally conscious market.
Wears it best
Fragrances featuring Globanone
Good to know
Questions, answered
The essentials on Globanone in perfumery: how it smells, where it comes from, and how it behaves on skin.
What is Globanone® and what type of musk is it?
Globanone® is a macrocyclic musk developed by Symrise through biotechnology. It belongs to the cyclohexadecanone family of musks, known for their clean, elegant scent profiles. Unlike traditional animal-derived musks, this ingredient is produced through sustainable biological processes.
When was Globanone® first produced commercially?
Symrise first produced Globanone® commercially in 2002 at their Bushy Park facility in the United Kingdom. Development began through research efforts in the late 1990s.
What does Globanone® smell like?
Globanone® offers a clean, sophisticated musk character. Perfumers describe it as elegant with smooth, creamy notes that blend well with floral and woody compositions. It functions as a fixative while contributing its own distinctive scent profile.
Why is Globanone® considered sustainable?
Globanone® is produced through biotechnology rather than traditional synthesis or natural extraction. This process reduces reliance on petrochemical feedstocks and eliminates the ethical concerns associated with animal-derived musks while maintaining consistent quality.
Is Globanone® solid at room temperature?
Yes, Globanone® is a white crystalline solid at room temperature. Fragrance suppliers typically offer it diluted to 50% in DPG (dipropylene glycol) for easier handling and formulation.
How does Globanone® differ from natural musks?
Natural musks like deer musk or ambrette require animal harvesting or plant extraction. Globanone® delivers a comparable clean musk scent through controlled biological production, offering perfumers a consistent, ethical alternative.
What products commonly contain Globanone®?
Fragrance houses incorporate Globanone® across fine fragrances, personal care products, and home care applications. Its versatility and sustainability profile make it popular in modern formulations seeking clean scent profiles.
How does biotech production improve fragrance ingredients?
Biotech production allows manufacturers to create specific molecular structures with precision, reducing unwanted byproducts. This approach delivers consistent quality batch to batch while maintaining lower environmental impact compared to traditional synthesis.










